What is gene therapy?

Gene therapy

"The ultimate goal of gene therapy is that the gene replacement therapy''.




Gene are the last word molecular switches that control various cellular process.The abnormal gene can manifest within the sort of specific gene disorders.until the last decade ,delivering gene into human to correct diseases has been accepted as scientifically viable and recognised as independent discipline and christened ''gene therapy''.

The ultimate source of gene therapy if the gene replacement therapy.Gene replacement therapy permits physiological regulation of the transgenes and elimination of the likelihood insertional inactivation of other of other cellular genes which occur at the time of random integration of the foreign gene.At present the present strategy for gene therapy largely centers around gene augmentation therapy,where the foreign gene replaces the defective or missing gene.

Overall, there are two strategy for gene transfer;(1) the in vivo approach which involves introduction of gene directly into the target organs of a private (it is completed in patients therefore,also called patient therapy), (2) ex vivo approach where cells are isolated for gene transfer in vitro followed by transplantation of genetically modified cell back to patients.

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